GPS2 anticorps (N-Term)
Aperçu rapide pour GPS2 anticorps (N-Term) (ABIN2789898)
Antigène
Voir toutes GPS2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- LKKVLHEEEK RRRKEQSDLT TLTSAAYQQS LTVHTGTHLL NMQGSPGGHN
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 91%, Zebrafish: 93%
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Attributs du produit
- This is a rabbit polyclonal antibody against Gps2. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N-terminal region of mouse GPS2
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- GPS2 (G Protein Pathway Suppressor 2 (GPS2))
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Autre désignation
- Gps2
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Sujet
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This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function.
Alias Symbols: AMF-1
Protein Size: 327 -
Poids moléculaire
- 37 kDa
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ID gène
- 2874
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NCBI Accession
- NM_004489, NP_004480
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UniProt
- Q13227
Antigène
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